Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264465 | 0.97 | MAPK1 (0.35) | MAPK1HTTSMN1; SMN2TLR7ADORA3 | |
| SCHEMBL21264467 | 0.92 | MAPK1 (0.32) | MAPK1HTTSMN1; SMN2TLR7LCK | |
| SCHEMBL21264466 | 0.92 | MAPK1 (0.32) | MAPK1HTTSMN1; SMN2TLR7LCK | |
| SCHEMBL19486094 | 0.87 | MAPK1 (0.44) | MAPK1HTTADORA3ADORA2AADORA1 | |
| SCHEMBL18083391 | 0.87 | MAPK1 (0.41) | MAPK1HTTSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL18083349 | 0.87 | MAPK1 (0.43) | MAPK1HTTSMN1; SMN2TLR7ADORA3 | |
| SCHEMBL21264692 | 0.87 | MAPK1 (0.33) | MAPK1HTTSMN1; SMN2ADORA1KDM4E | |
| SCHEMBL21264644 | 0.86 | LCK (0.31) | KDM4ELCKSRCKDR | |
| SCHEMBL12801006 | 0.85 | MAPK1 (0.42) | MAPK1HTTSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL21264786 | 0.85 | ALDH1A1 (0.39) | MAPK1HTTSMN1; SMN2ADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968229-B2 | Seven-membered ring compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | MCM7, XPO7, LUC7L2 | MAPK1 2190/4885HTT 2050/4885SMN1; SMN2 3354/4885 |
| US-10968229-B2 | Seven-membered ring compounds | MCM7, XPO7, LUC7L2 | MAPK1 2190/4885HTT 2050/4885SMN1; SMN2 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.