Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264787 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRPLA2G10L3MBTL1SMN1; SMN2 | |
| SCHEMBL21264464 | 0.92 | KDM4E (0.47) | ALDH1A1TSHRPLA2G10KMT2AGAA | |
| SCHEMBL23075524 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRPLA2G10KMT2AGAA | |
| SCHEMBL24171621 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TSHRPLA2G10KMT2APKM | |
| SCHEMBL21264472 | 0.87 | KDM4E (0.42) | ALDH1A1TSHRPLA2G10KMT2AGAA | |
| SCHEMBL21264594 | 0.85 | KDM4E (0.49) | ALDH1A1TSHRPLA2G10KMT2AGAA | |
| SCHEMBL20929428 | 0.85 | MAPK1 (0.35) | ALDH1A1TSHRPLA2G10KMT2ASMN1; SMN2 | |
| SCHEMBL21264465 | 0.85 | MAPK1 (0.35) | ALDH1A1TSHRPLA2G10KMT2ASMN1; SMN2 | |
| SCHEMBL21264776 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TSHRPLA2G10GAAKDM4E | |
| SCHEMBL21264739 | 0.84 | KDM4E (0.47) | ALDH1A1TSHRPLA2G10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147279-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | UDC IRELAND LIMITED (IE) | 2023-05-11 | — | — | US | disclosed |
| WO-2021185829-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-23 | — | — | WO | disclosed |
| US-20190252623-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190252623-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ZYX, NSD3, NES | ALDH1A1 3144/4885TSHR 3428/4885PLA2G10 3999/4885 |
| US-20230147279-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, VDAC2, KCNC1 | ALDH1A1 649/4885TSHR 4593/4885PLA2G10 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.