Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20967565 | 0.85 | MEN1 (0.34) | MEN1KMT2AATML3MBTL1MAPK14 | |
| SCHEMBL19257443 | 0.75 | CA12 (0.34) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL19721397 | 0.73 | MEN1 (0.34) | MEN1KMT2AATML3MBTL1MAPK14 | |
| SCHEMBL25464868 | 0.73 | L3MBTL1 (0.36) | MEN1KMT2AATML3MBTL1MAPK14 | |
| SCHEMBL18588506 | 0.69 | KDM4E (0.44) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL22808871 | 0.69 | L3MBTL1 (0.37) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL22627490 | 0.67 | L3MBTL1 (0.44) | MEN1KMT2AATML3MBTL1MAPK14 | |
| SCHEMBL19942086 | 0.66 | CCR1 (0.45) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL25464411 | 0.65 | L3MBTL1 (0.39) | MEN1KMT2AATML3MBTL1MAPK14 | |
| SCHEMBL23183282 | 0.65 | L3MBTL1 (0.39) | MEN1KMT2AATML3MBTL1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968229-B2 | Seven-membered ring compounds | IDEMITSU KOSAN CO., LTD. (JP) | 2021-04-06 | — | — | US | disclosed |
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119291-A1 | SEVEN-MEMBERED RING COMPOUNDS | MCM7, XPO7, LUC7L2 | MEN1 441/4885KMT2A 3830/4885ATM 4103/4885 |
| US-10968229-B2 | Seven-membered ring compounds | MCM7, XPO7, LUC7L2 | MEN1 441/4885KMT2A 3830/4885ATM 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.