SCHEMBL22627490

SCHEMBL22627490

C=Cc1c(C)oc2cccnc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ATM Q13315 2/20 0.44
HSP90AA1 P07900 2/20 0.37
NPC1 O15118 1/20 0.37
MAPK14 Q16539 1/20 0.33
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 2/20 0.33
CCR1 P32246 4/20 0.32
CCR8 P51685 4/20 0.32
HTT P42858 3/20 0.32
MAPT P10636 3/20 0.32
CCR5 P51681 3/20 0.32
GMNN O75496 1/20 0.32
TP53 P04637 1/20 0.32
MMP2 P08253 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19731908 0.85 L3MBTL1 (0.41) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL19731905 0.83 MEN1 (0.44) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL23183282 0.80 L3MBTL1 (0.39) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL1707915 0.73 HTT (0.46) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL21615029 0.71 KDM4E (0.47) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL6925972 0.70 KDM4E (0.48) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL25464868 0.69 L3MBTL1 (0.36) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL22373980 0.68 L3MBTL1 (0.39) L3MBTL1MEN1KMT2AATMHSP90AA1
SCHEMBL20929580 0.67 MEN1 (0.32) L3MBTL1MEN1KMT2AATMMAPK14
SCHEMBL21284878 0.66 BRD4 (0.42) L3MBTL1MEN1KMT2AATMHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 US disclosed
US-20230141433-A1 TRICYCLIC PESTICIDAL COMPOUNDS BASF CHEMICALS INDIA PVT. LTD. (IN) 2023-05-11 US disclosed
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
US-20220259242-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-08-18 US disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 US disclosed
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBP2 L3MBTL1 125/4885MEN1 4111/4885KMT2A 3297/4885
US-20220259242-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1LG2, CD274, L1CAM L3MBTL1 29/4885MEN1 710/4885KMT2A 2078/4885
US-20230141433-A1 TRICYCLIC PESTICIDAL COMPOUNDS DDT, ACHE, PFAS L3MBTL1 1778/4885MEN1 1586/4885KMT2A 3249/4885
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, KCNH3, KCNH2 L3MBTL1 607/4885MEN1 765/4885KMT2A 1410/4885
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 L3MBTL1 207/4885MEN1 2402/4885KMT2A 1024/4885
US-20230151039-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RPS4X, SOD1, CNKSR1 L3MBTL1 2019/4885MEN1 1699/4885KMT2A 2545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.