SCHEMBL19721397

SCHEMBL19721397

C=Nc1c(/C=C\C)oc2cccnc12

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20967565 0.85 MEN1 (0.34) MEN1KMT2AATML3MBTL1MAPK14
SCHEMBL19975710 0.75 L3MBTL1 (0.36) L3MBTL1
SCHEMBL20929580 0.73 MEN1 (0.32) MEN1KMT2AATML3MBTL1MAPK14
SCHEMBL19731905 0.70 MEN1 (0.44) MEN1KMT2AATML3MBTL1MAPK14
SCHEMBL19944330 0.69 LMNA (0.44) MEN1KMT2AL3MBTL1
SCHEMBL19731973 0.68 LIMK1 (0.34) MEN1KMT2A
SCHEMBL24300010 0.65 LMNA (0.46) MEN1KMT2AL3MBTL1
SCHEMBL25464411 0.65 L3MBTL1 (0.39) MEN1KMT2AATML3MBTL1MAPK14
SCHEMBL6925972 0.65 KDM4E (0.48) MEN1KMT2AATML3MBTL1MAPK14
SCHEMBL22627490 0.64 L3MBTL1 (0.44) MEN1KMT2AATML3MBTL1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2897959-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2017-12-20 EP disclosed