Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20932675 | 0.88 | SIGMAR1 (0.41) | SIGMAR1HRH3HTR1ASLC6A4GFER | |
| SCHEMBL20917798 | 0.84 | SLC6A4 (0.36) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20920181 | 0.83 | CYP1A2 (0.44) | SIGMAR1KMT2AGAACYP1A2CYP2D6 | |
| SCHEMBL20917919 | 0.82 | ALDH1A1 (0.44) | KMT2AGAAMAOBCYP1A2CYP2D6 | |
| SCHEMBL20920186 | 0.78 | CYP1A2 (0.49) | SIGMAR1KMT2AGAACYP1A2CYP3A4 | |
| SCHEMBL30130108 | 0.78 | KMT2A (0.45) | KMT2AKCNH2GAACYP1A2CYP2D6 | |
| SCHEMBL20932660 | 0.78 | KMT2A (0.45) | KMT2AKCNH2GAACYP1A2CYP2D6 | |
| SCHEMBL22262956 | 0.77 | ALDH1A1 (0.41) | SIGMAR1KMT2AGAAMAOBCYP1A2 | |
| SCHEMBL30130216 | 0.76 | CYP1A2 (0.45) | SIGMAR1GFERKMT2ACYP1A2CYP2D6 | |
| SCHEMBL20918290 | 0.76 | CYP1A2 (0.53) | GFERKMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | CANBAS CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| WO-2019078246-A1 | IDO/TDO INHIBITOR | 一般社団法人ファルマバレープロジェクト支援機構 | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239452-A1 | IDO/TDO Inhibitor | IDO1, IDO2, TDO2 | SIGMAR1 1856/4885HRH3 303/4885HTR1A 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.