SCHEMBL2093376

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2093377	0.80	EGFR (0.50)	EGFRP2RX1P2RX4P2RX7CES2
	SCHEMBL7978815	0.78	LMNA (0.58)	EGFRKMT2AMEN1IDO1CA12
	SCHEMBL15523018	0.78	EGFR (0.44)	EGFRP2RX1P2RX4P2RX7CES2
	SCHEMBL9833840	0.78	P2RX1 (0.47)	EGFRP2RX1P2RX4P2RX7CES2
	SCHEMBL2091319	0.78	EGFR (0.47)	EGFRCES2CES1CA1CA9
	SCHEMBL2910974	0.78	ALDH1A1 (0.61)	EGFRP2RX1P2RX4P2RX7CES2
	SCHEMBL2090931	0.78	MEN1 (0.69)	KMT2AMEN1IDO1RAB9ATSHR
	SCHEMBL2912001	0.76	MEN1 (0.55)	P2RX1P2RX4P2RX7CES2CES1
	SCHEMBL2091631	0.75	ALDH1A1 (0.64)	KMT2AMEN1CA12CA1CA9
	SCHEMBL8153587	0.75	ALDH1A1 (0.47)	EGFRP2RX1P2RX4P2RX7CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.