Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064405 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HTTKDM4EGAAMAPT | |
| SCHEMBL20934668 | 0.69 | ASGR1 (0.30) | — | |
| SCHEMBL16118629 | 0.67 | KDM4E (0.37) | ALDH1A1KDM4EGAA | |
| SCHEMBL11224012 | 0.67 | KDM4E (0.37) | ALDH1A1KDM4EGAA | |
| SCHEMBL31637665 | 0.67 | ALDH1A1 (0.36) | ALDH1A1HTTKDM4EGAAMAPT | |
| SCHEMBL31424427 | 0.67 | — | — | |
| SCHEMBL31637720 | 0.65 | ALDH1A1 (0.35) | ALDH1A1HTTKDM4EGAAMAPT | |
| SCHEMBL25857001 | 0.65 | EPHX2 (0.45) | KDM4E | |
| SCHEMBL31493470 | 0.64 | — | — | |
| SCHEMBL31493481 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137599-A1 | WRN INHIBITORS | NIMBUS WADJET, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250206738-A1 | WRN INHIBITORS | NIMBUS DISCOVERY, INC. | 2025-06-26 | — | — | US | disclosed |
| US-20250129069-A1 | TRIAZOLO WRN INHIBITORS | NIMBUS WADJET, INC. | 2025-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250206738-A1 | WRN INHIBITORS | WRN, BLM, RECQL | ALDH1A1 3002/4885HTT 958/4885KDM4E 3350/4885 |
| US-20250129069-A1 | TRIAZOLO WRN INHIBITORS | WRN, BLM, RECQL | ALDH1A1 3394/4885HTT 1152/4885KDM4E 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.