Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872652 | 0.92 | ALDH1A1 (0.51) | HPGDCYP2C19SNCAALDH1A1MAPT | |
| SCHEMBL19871235 | 0.81 | KMT2A (0.60) | CYP2C19SNCAALDH1A1MAPTHTR1D | |
| SCHEMBL18029007 | 0.81 | KMT2A (0.60) | CYP2C19SNCAALDH1A1MAPTHTR1D | |
| SCHEMBL3813966 | 0.78 | TRPV1 (0.66) | SNCAKDM4E | |
| SCHEMBL3810147 | 0.78 | TRPV1 (0.66) | SNCAKDM4E | |
| SCHEMBL21392230 | 0.77 | KIF11 (0.50) | HPGDALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL20119973 | 0.75 | LMNA (0.43) | CYP2C19ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL30402832 | 0.75 | HPGD (0.69) | HPGDCYP2C19ALDH1A1HTR1DHTR1B | |
| SCHEMBL3093023 | 0.75 | JAK2 (0.52) | ALDH1A1MAPTLMNAKMT2AKDM4E | |
| SCHEMBL30964171 | 0.74 | MAPT (0.80) | HPGDCYP2C19ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | CYP4F2, CYP2F1, POR | HPGD 260/4885CYP2C19 48/4885SNCA 2727/4885 |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, CYP2F1, POR | HPGD 260/4885CYP2C19 48/4885SNCA 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.