SCHEMBL209358

SCHEMBL209358

Cc1cc(C(=O)C2C(=O)CCCC2=O)c(C)c2c1SCc1cn(C)nc1-2

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SPR P35270 1/20 0.55
DRD4 P21917 3/20 0.40
DRD2 P14416 1/20 0.40
MMP12 P39900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8511068 0.91 SPR (0.64) SPRDRD4DRD2MMP12
SCHEMBL8726198 0.90 SPR (0.48) SPRDRD4DRD2MMP12
SCHEMBL8508639 0.87 SPR (0.42) SPR
SCHEMBL8508671 0.83 SPR (0.67) SPRDRD4DRD2
SCHEMBL8508676 0.79 DRD2 (0.46) SPRDRD4DRD2
SCHEMBL8511468 0.79 SPR (0.38) SPR
SCHEMBL8508310 0.74 MMP12 (0.35) SPRDRD4DRD2MMP12
SCHEMBL8559620 0.73 SPR (0.33) SPR
SCHEMBL8724257 0.71 SPR (0.34) SPR
SCHEMBL8726213 0.70 SPR (0.33) SPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140130206-A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM PIONEER HI-BRED INTERNATIONAL INC (US) 2014-05-08 US disclosed
US-8658858-B2 Polynucleotides encoding proteins involved in plant metabolism E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-02-25 US disclosed
US-20140031521-A1 PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2014-01-30 US disclosed
US-8637732-B2 Plant MYB transcription factor homologs E. I. DU NEMOURS AND COMPANY (US) 2014-01-28 US disclosed
US-20130007912-A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM EI DU PONT DE NEMOURS AND COMPANY; AND PIONEER HI-BRED INTERNATIONAL INC (US) 2013-01-03 US disclosed
US-8288616-B2 Polynucleotides encoding proteins involved in plant metabolism E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-10-16 US disclosed
US-20120110694-A1 PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS E. I. DU PONT DE NEMOURS AND COMPANY 2012-05-03 US disclosed
US-8088973-B2 Plant Myb transcription factor homologs E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
US-20110214204-A1 POLYNUCLEOTIDES ENCODING PROTEINS INVOLVED IN PLANT METABOLISM EI DU PONT DE NEMOURS AND COMPANY; AND PIONEER HI-BRED INTERNATIONAL INC (US) 2011-09-01 US disclosed
US-7943822-B2 Polynucleotides encoding proteins involved in plant metabolism E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-17 US disclosed
EP-1071793-A2 TRYPTOPHAN BIOSYNTHETIC ENZYMES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-31 EP disclosed
EP-1062355-A1 INHIBITORS OF APOPTOSIS PROTEINS IN PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-27 EP disclosed
WO-2000075340-A2 MAGNESIUM CHELATASE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-12-14 WO disclosed
WO-2000032791-A2 PLAN LECITHIN:CHOLESTEROL ACYLTRANSFERASES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-08 WO disclosed
WO-2000024915-A2 PLANT RAFFINOSE SYNTHASE HOMOLOGS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-04 WO disclosed
WO-2000005353-A2 CHORISMATE SYNTHASE FROM PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-02-03 WO disclosed
WO-2000004161-A1 GENES ENCODING SULFATE ASSIMILATION PROTEINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-01-27 WO disclosed
US-5985799-A TRICYCLIC N-HETEROCYCLES, THEIR N-OXIDES, AGRICULTURALLY-SUITABLE SALTS AND COMPOSITIONS, AND METHODS OF THEIR USE FOR CONTROLLING UNDESIRABLE VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-16 US disclosed
WO-1999049058-A2 TRYPTOPHAN BIOSYNTHETIC ENZYMES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-30 WO disclosed
WO-1999047688-A1 INHIBITORS OF APOPTOSIS PROTEINS IN PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-23 WO disclosed