Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 11/20 | 0.71 |
| ▸ | TLK2 | Q86UE8 | 5/20 | 0.66 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.66 |
| ▸ | JAK3 | P52333 | 3/20 | 0.66 |
| ▸ | CDK1 | P06493 | 1/20 | 0.61 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.61 |
| ▸ | NEK2 | P51955 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368518 | 0.83 | PAK4 (0.75) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL25738 | 0.81 | PAK4 (0.77) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL20944 | 0.80 | TLK2 (1.00) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL20945 | 0.80 | TLK2 (1.00) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL5363197 | 0.80 | TLK2 (0.80) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL12473990 | 0.80 | PAK4 (0.78) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL12473995 | 0.80 | PAK4 (0.78) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL13080513 | 0.79 | TLK2 (1.00) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL5361523 | 0.78 | PDPK1 (1.00) | PAK4TLK2PDPK1JAK3CDK1 | |
| SCHEMBL5728671 | 0.78 | PDPK1 (1.00) | PAK4TLK2PDPK1JAK3CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025726-A1 | Novel Hybrid Compounds | UNIVERSITY OF GREENWICH (GB) | 2012-03-01 | — | — | WO | disclosed |