Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937264 | 0.80 | LMNA (0.53) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL20937443 | 0.80 | LMNA (0.48) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL20937928 | 0.80 | ADORA3 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30276208 | 0.80 | LMNA (0.48) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL12852739 | 0.77 | MEN1 (0.51) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL18773577 | 0.74 | CA12 (0.62) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL1424853 | 0.73 | MEN1 (0.48) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL30276226 | 0.72 | CA12 (0.43) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL28404175 | 0.72 | CA12 (0.43) | LMNAHTTMEN1KMT2ARAB9A | |
| SCHEMBL18258941 | 0.72 | HTT (0.46) | LMNAHTTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |