Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21573059 | 0.68 | RAB9A (0.38) | ALDH1A1RXFP1NPC1RAB9ARECQL | |
| SCHEMBL10237052 | 0.68 | RAB9A (0.41) | ALDH1A1NPC1RAB9ARECQLL3MBTL1 | |
| SCHEMBL423145 | 0.67 | RAB9A (0.47) | ALDH1A1NPC1RAB9ARECQLL3MBTL1 | |
| SCHEMBL20267932 | 0.66 | NPC1 (0.58) | ALDH1A1NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL2498385 | 0.65 | NPC1 (0.72) | ALDH1A1NPC1RAB9AKDM4EHTT | |
| SCHEMBL211358 | 0.64 | RXFP1 (0.50) | ALDH1A1RXFP1NPC1RAB9ARECQL | |
| SCHEMBL13754002 | 0.64 | NPC1 (0.59) | ALDH1A1NPC1RAB9ARECQLL3MBTL1 | |
| SCHEMBL22726292 | 0.63 | MAPT (0.52) | ALDH1A1RXFP1NPC1RAB9ARECQL | |
| SCHEMBL27207717 | 0.63 | RAB9A (0.41) | ALDH1A1NPC1RAB9ARECQLL3MBTL1 | |
| SCHEMBL5776775 | 0.63 | ALDH1A1 (0.38) | ALDH1A1RAB9ARECQLL3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |