SCHEMBL211358

SCHEMBL211358

CC(=O)c1sc(C)nc1C

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
ALDH1A1 P00352 6/20 0.49
RAB9A P51151 5/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
RECQL P46063 1/20 0.49
HPGD P15428 1/20 0.47
MAPT P10636 2/20 0.46
NPC1 O15118 3/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
CNR1 P21554 1/20 0.45
DHODH Q02127 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6121613 0.98 SMN1; SMN2 (0.49) RXFP1GAAL3MBTL1CYP1A2CYP2C9
Hydrochlorthiazide SCHEMBL15796732 0.81 ALDH1A1 (0.41) RXFP1GAAL3MBTL1CYP1A2CYP2C9
SCHEMBL286332 0.81 ALDH1A1 (0.63) GAAL3MBTL1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL423145 0.79 RAB9A (0.47) GAAL3MBTL1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL10672138 0.79 ALDH1A1 (0.49) RXFP1GAAL3MBTL1CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL9528992 0.79 ALDH1A1 (0.61) GAAL3MBTL1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL3344131 0.79 CNR1 (0.47) GAAL3MBTL1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL1477812 0.79 RAB9A (0.47) GAAL3MBTL1CYP1A2ALDH1A1RAB9A
SCHEMBL13165457 0.79 RXFP1 (0.49) RXFP1GAAL3MBTL1CYP1A2CYP2C9
SCHEMBL289401 0.79 RXFP1 (0.49) RXFP1GAAL3MBTL1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118166368-A Method for electrochemically synthesizing 2, 4-dimethyl-5-acetylthiazole 江西师范大学 2024-06-11 CN claimed
US-20220370615-A1 Prevention of Illicit Manufacture of Methamphetamine from Pseudoephedrine Using Food Flavor Excipients Satara Pharmaceuticals (US) 2022-11-24 US claimed
CN-114790548-A Palladium removing liquid for printed circuit board, palladium removing method and preparation method of printed circuit board 深圳市板明科技股份有限公司 2022-07-26 CN claimed
CN-108618097-B Salted egg yolk essence 广州华宝食品有限公司 2021-07-27 CN claimed
EP-3809876-A1 PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME PERPRIN S.R.L. (IT) 2021-04-28 EP claimed
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound HENKEL AG & CO. KGAA (DE) 2021-02-16 US claimed
US-20200146960-A1 Antiperspirant and Deodorant Compositions PROCTER & GAMBLE (US) 2020-05-14 US claimed
US-10568825-B2 Antiperspirant and deodorant compositions THE PROCTER & GAMBLE COMPANY (US) 2020-02-25 US claimed
WO-2019243869-A1 PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME PERPRIN S.R.L. (IT) 2019-12-26 WO claimed
CN-108936547-A A kind of \"Zongzi\" flavour and preparation method thereof 河南创新研霖食品科技有限公司 2018-12-07 CN claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673784-B1 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORP (US) 1999-10-27 EP claimed
US-5665504-A Simulated photographic-quality prints using a plasticizer to reduce curl XEROX CORPORATION (US) 1997-09-09 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673784-A2 Recording sheets containing oxazole, isooxazole, oxazolidinone, oxazoline salts, morpholine, thiazole, thiazolidine, thiadiazole, and phenothiazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-RE29843-E Substituted thiazoles and flavoring processes and products produced thereby INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US claimed
US-4093752-A FOODSTUFFS, CHEWING GUM, TOOTHPASTE, MEDICINES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10568825-B2 Antiperspirant and deodorant compositions DEK, QDPR, GPX4 RXFP1 4826/4885GAA 3418/4885L3MBTL1 3421/4885
US-20220370615-A1 Prevention of Illicit Manufacture of Methamphetamine from Pseudoephedrine Using Food Flavor Excipients MCHR1, TAAR5, COMT RXFP1 3171/4885GAA 989/4885L3MBTL1 3069/4885
US-10920176-B2 Transparent liquids, in particular fabric treatment agents, comprising perfume and microcapsules with an odor modulator compound NEFM, TRPA1, ALOX5 RXFP1 2762/4885GAA 3613/4885L3MBTL1 2305/4885
US-20200146960-A1 Antiperspirant and Deodorant Compositions DEK, QDPR, GPX4 RXFP1 4826/4885GAA 3418/4885L3MBTL1 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.