Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369633 | 0.88 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5369625 | 0.87 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL3856253 | 0.83 | SMN1; SMN2 (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1251880 | 0.82 | KDM4E (0.53) | KMT2AMEN1ATMKDM4ESMN1; SMN2 | |
| SCHEMBL206952 | 0.82 | MEN1 (0.57) | KMT2AMEN1ATMNPC1ALDH1A1 | |
| SCHEMBL11453114 | 0.82 | ALDH1A1 (0.56) | KMT2AATMNPC1ALDH1A1RAB9A | |
| SCHEMBL6560866 | 0.82 | HIF1A (0.56) | KMT2AATMNPC1ALDH1A1RAB9A | |
| SCHEMBL3498807 | 0.82 | BCHE (0.67) | KMT2AMEN1NPC1BCHERAB9A | |
| SCHEMBL548 | 0.81 | LTA4H (0.64) | BCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL11684699 | 0.81 | ALDH1A1 (0.74) | ATMNPC1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444237-B1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| EP-3444237-A1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | Chai Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017162156-A1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | 正大天晴药业集团股份有限公司 | 2017-09-28 | — | — | WO | disclosed |
| US-8088923-B2 | Cyclic-fused beta-lactones and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088923-B2 | Cyclic-fused beta-lactones and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090062547-A1 | CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS | THE TEXAS A&M UNIVERSITY SYSTEM | 2009-03-05 | — | — | US | disclosed |
| US-20090062547-A1 | CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS | THE TEXAS A&M UNIVERSITY SYSTEM | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062547-A1 | CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS | COASY, FASN, OTUB1 | KMT2A 2478/4885MEN1 3332/4885ATM 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.