Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150588 | 0.84 | ALDH1A1 (0.56) | ALDH1A1FFAR1FFAR4MRGPRX4MAOA | |
| SCHEMBL18641314 | 0.84 | LMNA (0.42) | FFAR1HCAR2PTPN1FFAR4CA12 | |
| SCHEMBL4773202 | 0.84 | ALDH1A1 (0.56) | ALDH1A1FFAR1PTPN1FFAR4CA2 | |
| SCHEMBL17283451 | 0.80 | ALDH1A1 (0.58) | ALDH1A1FFAR1MEN1KMT2ATDP1 | |
| SCHEMBL134801 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HCAR2MMP1MMP2MMP9 | |
| SCHEMBL11226742 | 0.75 | ALDH1A1 (0.61) | ALDH1A1FFAR1HCAR2FFAR4MMP1 | |
| SCHEMBL28046532 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HCAR2MMP1MMP2MMP9 | |
| SCHEMBL11237868 | 0.75 | ALDH1A1 (0.61) | ALDH1A1FFAR4MMP2MMP9MMP12 | |
| SCHEMBL3764644 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HCAR2MMP1MMP2MMP9 | |
| SCHEMBL960 | 0.73 | ALDH1A1 (1.00) | ALDH1A1HCAR2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787877-B2 | Antibody with non-natural amino acid introduced therein | RIKEN (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20210107997-A1 | ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN | RIKEN (JP) | 2021-04-15 | — | — | US | disclosed |
| US-10906990-B2 | Antibody with non-natural amino acid introduced therein | RIKEN (JP) | 2021-02-02 | — | — | US | disclosed |
| US-20190127488-A1 | ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN | RIKEN (JP) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127488-A1 | ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN | NSUN3, NSUN2, LNPEP | ALDH1A1 4169/4885FFAR1 3776/4885HCAR2 3604/4885 |
| US-10906990-B2 | Antibody with non-natural amino acid introduced therein | NSUN3, NSUN2, LNPEP | ALDH1A1 4169/4885FFAR1 3776/4885HCAR2 3604/4885 |
| US-20210107997-A1 | ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN | NSUN3, NSUN2, LNPEP | ALDH1A1 4169/4885FFAR1 3776/4885HCAR2 3604/4885 |
| US-11787877-B2 | Antibody with non-natural amino acid introduced therein | NSUN3, NSUN2, LNPEP | ALDH1A1 4169/4885FFAR1 3776/4885HCAR2 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.