Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.40 |
| ▸ | NQO2 | P16083 | 5/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5392965 | 0.87 | — | — | |
| SCHEMBL9257155 | 0.81 | EPHX2 (0.41) | MTNR1AMTNR1BNQO2EPHX1KDM4E | |
| SCHEMBL2091382 | 0.79 | KDM4E (0.41) | MTNR1AMTNR1BNQO2EPHX1KDM4E | |
| SCHEMBL8392768 | 0.79 | EPHX1 (0.52) | MTNR1AMTNR1BNQO2EPHX1KDM4E | |
| SCHEMBL6707040 | 0.79 | EPHX1 (0.56) | MTNR1AMTNR1BEPHX1KDM4EMAPK1 | |
| SCHEMBL931424 | 0.77 | EPHX1 (0.59) | EPHX1KDM4EMAPK1HIF1ATSHR | |
| SCHEMBL8392277 | 0.77 | EPHX1 (0.59) | EPHX1KDM4EMAPK1HIF1ATSHR | |
| SCHEMBL9259909 | 0.77 | ITGB3 (0.36) | MTNR1AMTNR1BNQO2EPHX1 | |
| SCHEMBL15250149 | 0.75 | EPHX1 (0.38) | MTNR1AMTNR1BNQO2EPHX1KDM4E | |
| SCHEMBL8392280 | 0.75 | KDM4E (0.56) | MTNR1AMTNR1BNQO2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951073-B2 | Compounds and compositions for treating chemical warfare agent-induced injuries | HYDRA BIOSCIENCES, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-8163761-B2 | Methods and compositions for treating disorders | HYDRA BIOSCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303521-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | MTNR1A 1034/4885MTNR1B 1170/4885NQO2 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.