Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FURIN | P09958 | 2/20 | 0.42 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.41 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPA2 | P48052 | 2/20 | 0.36 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20950949 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL22367094 | 1.00 | ALDH1A1 (0.50) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL20965281 | 0.91 | FURIN (0.48) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL20965523 | 0.90 | SIRT6 (0.52) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL30493601 | 0.89 | ALDH1A1 (0.58) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL14932683 | 0.89 | ALDH1A1 (0.58) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL22367131 | 0.87 | ALDH1A1 (0.53) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL20951073 | 0.87 | ALDH1A1 (0.53) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL20951072 | 0.87 | ALDH1A1 (0.53) | ALDH1A1FURINPCSK6SIRT5KISS1R | |
| SCHEMBL20951903 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SIRT5KISS1RPTPN1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046729-B2 | Dipeptide analogs as TGF-beta inhibitors | SOUTHERN RESEARCH INSTITUTE (US) | 2021-06-29 | — | — | US | disclosed |
| EP-3700545-A1 | DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS | Southern Research Institute (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20190127420-A1 | DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS | UAB RESEARCH FOUNDATION | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127420-A1 | DIPEPTIDE ANALOGS AS TGF-BETA INHIBITORS | TGFB1, TGFB2, SMAD3 | ALDH1A1 3575/4885FURIN 1051/4885PCSK6 2898/4885 |
| US-11046729-B2 | Dipeptide analogs as TGF-beta inhibitors | TGFB1, TGFB2, SMAD3 | ALDH1A1 3575/4885FURIN 1051/4885PCSK6 2898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.