SCHEMBL2095116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2089543	0.98	HAO1 (0.47)	HRH3HAO1KCNH2HDAC1HDAC8
	SCHEMBL19615123	0.81	HRH3 (0.48)	HRH3HAO1KCNH2SMN1; SMN2ESR2
	SCHEMBL781509	0.80	HDAC1 (0.54)	HAO1HDAC1HDAC8HDAC6MAPT
	SCHEMBL6704196	0.79	HAO1 (0.59)	HRH3HAO1KCNH2HDAC1HDAC8
	SCHEMBL28850514	0.77	HAO1 (0.53)	HRH3HAO1KCNH2HDAC1HDAC8
	SCHEMBL2095118	0.77	ALDH1A1 (0.56)	HRH3HAO1KCNH2MAPTALDH1A1
	SCHEMBL5147779	0.77	ESR2 (0.54)	HAO1HDAC1HDAC8HDAC6MAPT
	SCHEMBL15260520	0.77	HDAC8 (0.52)	HRH3HAO1KCNH2HDAC1HDAC8
	SCHEMBL6275125	0.77	HDAC8 (0.52)	HRH3HAO1KCNH2HDAC1HDAC8
	SCHEMBL28584923	0.77	HDAC8 (0.52)	HRH3HAO1KCNH2HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.