SCHEMBL2095196

SCHEMBL2095196

C=C(C)C(=O)OCC.CN(C)CCC(O)S(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
TSHR P16473 4/20 0.37
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.31
GLO1 Q04760 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095192 0.87 THRB (0.37) THRBTSHRCYP2D6CYP2C19ALDH1A1
SCHEMBL865210 0.79 THRB (0.42) THRBTSHRCYP2D6CYP2C19ALDH1A1
N,N-Dimethylethanaminium SCHEMBL7866527 0.78 THRB (0.47) THRBTSHRALDH1A1GAAGLO1
N,N-Dimethylethanaminium SCHEMBL8023992 0.78 THRB (0.47) THRBTSHRALDH1A1GAAGLO1
N,N-Dimethylethanaminium SCHEMBL8023985 0.78 THRB (0.47) THRBTSHRALDH1A1GAAGLO1
Sulfuric Acid SCHEMBL631032 0.78 THRB (0.50) THRBTSHRALDH1A1GAAGLO1
SCHEMBL28578016 0.78
SCHEMBL1573668 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL1067255 0.77 THRB (0.46) THRBTSHRALDH1A1
SCHEMBL152823 0.77 THRB (0.40) THRBTSHRALDH1A1GAAGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318871-B2 Process for preparing a polymer RHODIA OPERATIONS (FR) 2012-11-27 US disclosed
US-8163100-B2 Synthetic microgel polymer compositions for treating and/or modifying hard surfaces RHODIA OPERATIONS (FR) 2012-04-24 US disclosed
US-20100152395-A1 PROCESS FOR PREPARING A POLYMER RHODIA OPERATIONS (FR) 2010-06-17 US disclosed
US-20100004152-A1 Synthetic Microgel Polymer Compositions for Treating and/or Modifying Hard Surfaces RHODIA OPERATIONS (FR) 2010-01-07 US disclosed