Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19520573 | 0.96 | KMT2A (0.62) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL20952220 | 0.93 | POLB (0.67) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL19538809 | 0.86 | ALDH1A1 (0.72) | KMT2AMEN1ALDH1A1NPSR1USP2 | |
| SCHEMBL24021619 | 0.82 | KMT2A (0.57) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL17725786 | 0.82 | TSHR (0.61) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL17725589 | 0.81 | USP2 (0.60) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL23289826 | 0.81 | TSHR (0.61) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL17725594 | 0.81 | TSHR (0.61) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL17725602 | 0.81 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1LMNANPSR1 | |
| SCHEMBL17725609 | 0.81 | TSHR (0.60) | KMT2AMEN1ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127360-A1 | COMPOUNDS FOR MODULATING AQUAPORINS | APOGLYX AB (SE) | 2019-05-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127360-A1 | COMPOUNDS FOR MODULATING AQUAPORINS | AQP1, AQP4, AQP3 | KMT2A 4594/4885MEN1 1406/4885ALDH1A1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.