Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20955868 | 1.00 | ALDH1A1 (0.35) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20955878 | 0.91 | PAM (0.40) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20955880 | 0.91 | PAM (0.40) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20955879 | 0.91 | PAM (0.40) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20980102 | 0.86 | SMN1; SMN2 (0.38) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20955914 | 0.81 | KMT2A (0.36) | ALDH1A1MAPTKMT2AHPGDLMNA | |
| SCHEMBL20955883 | 0.81 | GRIK1 (0.36) | ALDH1A1RAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL20955865 | 0.81 | GRIK1 (0.36) | ALDH1A1RAB9AMAPTNPC1KMT2A | |
| SCHEMBL20955912 | 0.81 | KMT2A (0.36) | ALDH1A1MAPTKMT2AHPGDLMNA | |
| SCHEMBL20955866 | 0.81 | GRIK1 (0.36) | ALDH1A1RAB9AMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480190-B1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INST OF TECHN (US) | 2023-01-04 | — | — | EP | disclosed |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-13 | — | — | US | disclosed |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-23 | — | — | US | disclosed |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2019-05-09 | — | — | US | disclosed |
| EP-3480190-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | California Institute of Technology (US) | 2019-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048201-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | ALDH1A1 265/4885RAB9A 1880/4885MAPT 4392/4885 |
| US-20190135754-A1 | METHODS FOR ENANTIOSELECTIVE ALLYLIC ALKYLATION OF ESTERS, LACTONES, AND LACTAMS WITH UNACTIVATED ALLYLIC ALCOHOLS | LSS, COASY, ADH1A | ALDH1A1 265/4885RAB9A 1880/4885MAPT 4392/4885 |
| US-10745354-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | ALDH1A1 265/4885RAB9A 1880/4885MAPT 4392/4885 |
| US-10358422-B2 | Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols | LSS, COASY, ADH1A | ALDH1A1 265/4885RAB9A 1880/4885MAPT 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.