Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14378012 | 0.90 | MMP9 (0.33) | GRIN1GRIN2AMMP9 | |
| SCHEMBL21408162 | 0.88 | MMP9 (0.32) | MMP9 | |
| Tert-Butyl Formate SCHEMBL28026716 | 0.84 | TDP1 (0.35) | GRIN1GRIN2A | |
| SCHEMBL6942322 | 0.83 | LMNA (0.40) | GRIN1GRIN2AHPGDPOLBMMP9 | |
| SCHEMBL14378048 | 0.83 | LMNA (0.40) | GRIN1GRIN2AHPGDPOLBMMP9 | |
| SCHEMBL14554863 | 0.83 | — | — | |
| SCHEMBL22007692 | 0.80 | — | — | |
| SCHEMBL14378055 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL14378009 | 0.78 | MMP9 (0.32) | GRIN1GRIN2AMMP9 | |
| SCHEMBL14378098 | 0.78 | GRIN1 (0.34) | GRIN1GRIN2AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531715-B | RSV antiviral pyrazolo-and triazolo-pyrimidine compounds | 爱尔兰詹森科学公司 | 2021-03-30 | — | — | CN | disclosed |
| EP-3288942-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | Janssen Sciences Ireland UC (IE) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016174079-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-11-03 | — | — | WO | disclosed |
| WO-2015094803-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-0417143-A1 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011856-A2 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |