SCHEMBL20958247

SCHEMBL20958247

C=CC(C)(C)c1cc(C(c2ccc(O)c(C(C)(C)C=C)c2)(C(F)(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 4/20 0.40
▸ ESR2 Q92731 3/20 0.40
▸ ALDH1A1 P00352 5/20 0.38
▸ ALOX15 P16050 3/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ NR1I2 O75469 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ MIF P14174 1/20 0.38
▸ TYR P14679 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ NFE2L2 Q16236 1/20 0.38
▸ PTPN1 P18031 5/20 0.36
▸ AR P10275 2/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ PDE4D Q08499 1/20 0.34
▸ IDH1 O75874 1/20 0.34
▸ ABCB1 P08183 1/20 0.34
▸ UGT1A1 P22309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24652551 0.88 PTPN1 (0.33) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL17300225 0.83 ALDH1A1 (0.55) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL18399455 0.78 ALDH1A1 (0.46) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL7769611 0.75 ESR1 (0.48) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL17298627 0.75 ALDH1A1 (0.47) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL20958250 0.75 ESR1 (0.41) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL25933462 0.75 ESR1 (0.60) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL29404885 0.75 ESR1 (0.59) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL29925195 0.75 ESR1 (0.59) ESR1ESR2ALDH1A1ALOX15HSD17B10
SCHEMBL3688722 0.75 ESR1 (0.59) ESR1ESR2ALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779901-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-10-10 — — US disclosed
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-08-29 — — US disclosed
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-23 — — US disclosed
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-16 — — US disclosed
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 — — US disclosed
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 — — US disclosed
US-20220250032-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-11 — — US disclosed
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-04 — — US disclosed
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-05-10 — — US disclosed
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-05-10 — — US disclosed
EP-3706899-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS The Government Of The United States Of America As The Secretary of The Navy (US) 2020-09-16 — — EP disclosed
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-20220250032-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-11779901-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885ALDH1A1 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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