Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24736765 | 0.80 | POLRMT (0.36) | POLRMTDOT1L | |
| SCHEMBL24737136 | 0.80 | POLRMT (0.36) | POLRMTDOT1L | |
| SCHEMBL25853155 | 0.80 | POLRMT (0.38) | POLRMTDOT1LTNK2 | |
| SCHEMBL25300989 | 0.80 | POLRMT (0.38) | POLRMTDOT1LTNK2 | |
| SCHEMBL25254465 | 0.80 | POLRMT (0.38) | POLRMTDOT1LTNK2 | |
| SCHEMBL19101790 | 0.79 | POLRMT (0.36) | POLRMTDOT1LTNK2 | |
| SCHEMBL24736798 | 0.77 | POLRMT (0.34) | POLRMTDOT1LTNK2 | |
| SCHEMBL24736764 | 0.76 | POLRMT (0.35) | POLRMTDOT1LTNK2 | |
| SCHEMBL16701318 | 0.75 | POLRMT (0.35) | POLRMT | |
| SCHEMBL19779069 | 0.75 | DOT1L (0.35) | POLRMTDOT1LTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |