SCHEMBL20960987

SCHEMBL20960987

Nc1ccc2c(c1)c1ccc3ccccc3c1n2-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 4/20 0.41
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
HBB P68871 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 1/20 0.41
NPC1 O15118 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
CYP3A4 P08684 2/20 0.38
FGFR1 P11362 1/20 0.37
ALOX15 P16050 2/20 0.37
CASP1 P29466 2/20 0.37
CASP7 P55210 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257051 0.90 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL10043622 0.86 KDM4E (0.53) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL10061173 0.82 L3MBTL1 (0.61) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL18627660 0.82 L3MBTL1 (0.44) KDM4EMEN1MAPTKMT2AL3MBTL1
SCHEMBL16906000 0.82 MAOA (0.44) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL25487722 0.82 ALDH1A1 (0.42) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL19132476 0.82 HPRT1 (0.41) ALDH1A1KDM4EHSD17B10KMT2ATDP1
SCHEMBL12126569 0.82 L3MBTL1 (0.41) ALDH1A1KDM4EMEN1KMT2AL3MBTL1
SCHEMBL17989787 0.82 L3MBTL1 (0.56) ALDH1A1KDM4EHSD17B10MEN1MAPT
SCHEMBL26166833 0.82 PRKDC (0.39) ALDH1A1KDM4EHSD17B10MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3476833-B1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-10-14 EP disclosed
EP-3476833-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-05-01 EP disclosed