SCHEMBL20964153

SCHEMBL20964153

O=C(c1ccccc1)c1ccc(-c2cc3nc(n2)-c2cccc(c2)-c2cccc(c2)N(c2ccccc2)c2cccc(c2)-c2cccc-3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.44
MEN1 O00255 6/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPT P10636 5/20 0.44
HPGD P15428 5/20 0.44
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
CYP2C19 P33261 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
RECQL P46063 1/20 0.43
NTSR1 P30989 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
KMO O15229 1/20 0.42
ADORA1 P30542 2/20 0.42
GLA P06280 1/20 0.42
HPSE Q9Y251 1/20 0.40
ADORA3 P0DMS8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20964188 0.91 ATM (0.42) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL20962302 0.88 MEN1 (0.56) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964192 0.86 MEN1 (0.51) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964240 0.81 MEN1 (0.45) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964243 0.81 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964239 0.79 MEN1 (0.47) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964238 0.78 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964241 0.78 MEN1 (0.46) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20964172 0.77 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1MAPTHPGD
SCHEMBL20149978 0.77 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10930858-B2 Nitrogen-containing compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-23 US disclosed
US-20190131534-A1 NITROGEN-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190131534-A1 NITROGEN-CONTAINING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME NOS1, DNTT, NOS2 KMT2A 2048/4885MEN1 1561/4885ALDH1A1 2261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.