Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20964446 | 1.00 | ACE (0.62) | ACEF2ACE2OPRK1STAT6 | |
| SCHEMBL10679400 | 0.85 | ACE (0.66) | ACEACE2 | |
| SCHEMBL20964447 | 0.83 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL20964445 | 0.83 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL29666779 | 0.81 | ACE (0.62) | ACEF2ACE2OPRK1 | |
| SCHEMBL31621499 | 0.81 | ACE (0.64) | ACEF2ACE2OPRK1 | |
| SCHEMBL10668559 | 0.81 | ACE (0.68) | ACEACE2 | |
| SCHEMBL30398539 | 0.81 | F2 (0.59) | F2OPRK1STAT6 | |
| SCHEMBL8250626 | 0.80 | OPRM1 (0.60) | ACEOPRK1 | |
| SCHEMBL9551626 | 0.80 | ACE (0.66) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | RESEARCH TRIANGLE INSTITUTE (US) | 2022-01-11 | — | — | US | disclosed |
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RESEARCH TRIANGLE INSTITUTE | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127419-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NPSR1, GRPR, NPBWR1 | ACE 1354/4885F2 1628/4885ACE2 2700/4885 |
| US-11220526-B2 | Neuropeptide S receptor (NPSR) agonists | NPSR1, GRPR, NPBWR1 | ACE 1354/4885F2 1628/4885ACE2 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.