Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968232 | 0.90 | CHUK (0.56) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL20968205 | 0.89 | S1PR1 (0.54) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL20968189 | 0.88 | RAB9A (0.47) | S1PR1LMNANPC1RAB9ANR1H4 | |
| SCHEMBL20968275 | 0.86 | SMN1; SMN2 (0.52) | S1PR1CHUKTXNRD1NOX4NPC1 | |
| SCHEMBL20968272 | 0.86 | S1PR1 (0.56) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL20968198 | 0.84 | S1PR1 (0.55) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL3053264 | 0.84 | LMNA (0.60) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL3061859 | 0.82 | LMNA (0.62) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL13089335 | 0.82 | LMNA (0.62) | S1PR1CHUKTXNRD1NOX4S1PR3 | |
| SCHEMBL3070197 | 0.80 | LMNA (0.62) | S1PR1CHUKTXNRD1NOX4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662164-B2 | Non-beta lactam antibiotics | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | UNIVERSITY OF NOTRE DAME DU LAC | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662164-B2 | Non-beta lactam antibiotics | OXA1L, O60361, CUTA | S1PR1 2372/4885CHUK 2632/4885TXNRD1 2937/4885 |
| US-20190127340-A1 | NON-BETA LACTAM ANTIBIOTICS | OXA1L, O60361, CUTA | S1PR1 2372/4885CHUK 2632/4885TXNRD1 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.