Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20531764 | 1.00 | CES2 (0.36) | CES2CES1HTR2AHTR2CMC4R | |
| SCHEMBL21884017 | 0.86 | ACHE (0.41) | CES2CES1HTR2AHTR2C | |
| SCHEMBL19768998 | 0.82 | HTR2C (0.36) | HTR2AHTR2C | |
| SCHEMBL21884016 | 0.81 | HTR2A (0.30) | HTR2AHTR2C | |
| SCHEMBL19880513 | 0.81 | GABRA1 (0.39) | CES2CES1HTR2AHTR2CMC4R | |
| SCHEMBL19880514 | 0.77 | TSHR (0.40) | HTR2AHTR2CMC4R | |
| SCHEMBL18306095 | 0.74 | CYP1A2 (0.38) | — | |
| SCHEMBL20238028 | 0.74 | IDO1 (0.41) | CES2CES1 | |
| SCHEMBL20238027 | 0.74 | IDO1 (0.41) | CES2CES1 | |
| SCHEMBL29669053 | 0.74 | IDO1 (0.41) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481823-A1 | 7-SUBSTITUTED 1-PYRIDYL-NAPHTHYRIDINE-3-CARBOXYLIC ACID AMIDES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2019-05-15 | — | — | EP | disclosed |