Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.39 |
| ▸ | MGMT | P16455 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 4/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702158 | 0.79 | PIN1 (0.53) | PIN1MGMTCDK1CCNB1CDK2 | |
| Hydrochloric Acid SCHEMBL18605740 | 0.78 | PIN1 (0.52) | PIN1MGMTCDK1CCNB1CDK2 | |
| SCHEMBL27775483 | 0.75 | CDK1 (0.43) | PIN1MGMTCDK1CCNB1CDK2 | |
| SCHEMBL27503508 | 0.73 | CDK1 (0.50) | PIN1MGMTCDK1CCNB1CDK2 | |
| SCHEMBL17186555 | 0.71 | PIK3CA (0.40) | CDK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL20970003 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL17186643 | 0.71 | PIK3CA (0.39) | CDK2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17186533 | 0.69 | SMN1; SMN2 (0.42) | PIN1MGMTCDK1CCNB1CDK2 | |
| Hydrochloric Acid SCHEMBL18605766 | 0.68 | SMN1; SMN2 (0.42) | PIN1MGMTCDK1CCNB1CDK2 | |
| SCHEMBL28026664 | 0.67 | PNP (0.45) | PIN1MGMTCDK1CCNB1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981913-B2 | 11C -labeled 06 -benzylguanine, pet probe capable of visualizing 06-methyl guanine methyl-transferase activity, and production method of the same | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2021-04-20 | — | — | US | disclosed |
| US-20190308974-A1 | 11C -LABELED O6 -BENZYLGUANINE, PET PROBE CAPABLE OF VISUALIZING O6 -METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHOD OF THE SAME | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2019-10-10 | — | — | US | disclosed |
| EP-3483160-A1 | 11C-LABELLED O6-BENZYLGUANINE, POSITRON EMISSION TOMOGRAPHY (PET) PROBE CAPABLE OF VISUALIZING O6-METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHODS THEREFOR | National Center for Geriatrics and Gerontology (JP) | 2019-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190308974-A1 | 11C -LABELED O6 -BENZYLGUANINE, PET PROBE CAPABLE OF VISUALIZING O6 -METHYL GUANINE METHYL-TRANSFERASE ACTIVITY, AND PRODUCTION METHOD OF THE SAME | DIMT1, ICMT, NUDT1 | PIN1 1616/4885MGMT 24/4885CDK1 3266/4885 |
| US-10981913-B2 | 11C -labeled 06 -benzylguanine, pet probe capable of visualizing 06-methyl guanine methyl-transferase activity, and production method of the same | DIMT1, MPG, NUDT1 | PIN1 1405/4885MGMT 17/4885CDK1 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.