Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL20972306 | 1.00 | NAPRT (0.53) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22261964 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1407986 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL3316655 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL407438 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22261990 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL1005857 | 0.94 | NAPRT (0.60) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL25405557 | 0.91 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL122022 | 0.91 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B | |
| Pyridine SCHEMBL22151316 | 0.91 | NAPRT (0.56) | NAPRTTSHRTDP1CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190148754-A1 | USE OF IONIC LIQUIDS AS AN ADJUVANT IN ELECTROCHEMISTRY | UNIVERSITE DE RENNES 1 (FR) | 2019-05-16 | — | — | US | claimed |
| CN-109643817-A | Use of ionic liquids as adjuvants in electrochemistry | 雷恩第大学 | 2019-04-16 | — | — | CN | claimed |
| US-20190148754-A1 | USE OF IONIC LIQUIDS AS AN ADJUVANT IN ELECTROCHEMISTRY | UNIVERSITE DE RENNES 1 (FR) | 2019-05-16 | — | — | US | disclosed |
| CN-109643817-A | Use of ionic liquids as adjuvants in electrochemistry | 雷恩第大学 | 2019-04-16 | — | — | CN | disclosed |