Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.46 |
| ▸ | HTR1A | P08908 | 14/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605816 | 0.83 | CXCL8 (0.50) | SLC6A2HTR1AKDM4ESLC6A3SLC6A4 | |
| SCHEMBL3845701 | 0.77 | CA12 (0.38) | SLC6A2KDM4EMAPTCRHBPCRHR2 | |
| SCHEMBL1341306 | 0.75 | KDM4E (0.70) | SLC6A2HTR1AKDM4EMAPTCRHBP | |
| SCHEMBL26206573 | 0.75 | MAPT (0.48) | KDM4EMAPTCRHBPCRHR2 | |
| SCHEMBL3843330 | 0.74 | HTT (0.39) | SLC6A2HTR1ASLC6A3SLC6A4CXCL8 | |
| SCHEMBL16415975 | 0.74 | SLC6A2 (0.45) | SLC6A2HTR1ASLC6A3SLC6A4EPAS1 | |
| SCHEMBL5508654 | 0.73 | CXCL8 (0.46) | SLC6A2HTR1AKDM4EMAPTSLC6A3 | |
| SCHEMBL30159449 | 0.72 | TRPA1 (0.53) | SLC6A2SLC6A3SLC6A4EPAS1HSPB1 | |
| SCHEMBL3847171 | 0.70 | ALDH1A1 (0.52) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5647650 | 0.70 | KMT2A (0.38) | SLC6A2KDM4ESLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-214346097-U | Vortex formula 1, 3-difluoro-2- (2-iodophenoxy) benzene mixing arrangement is used in production | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-214346508-U | 1, 3-difluoro-2- (2-iodophenoxy) benzene production is with biological safety cabinet convenient to remove | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-213763173-U | Ultrasonic cleaning device is used in production of 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-213759594-U | Hot air disinfection cabinet for producing 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | claimed |
| EP-3455212-B1 | INHIBITORS OF PROTEASE-ACTIVATED RECEPTOR-2 | HEPTARES THERAPEUTICS LTD (GB) | 2022-02-09 | — | — | EP | disclosed |
| CN-214346097-U | Vortex formula 1, 3-difluoro-2- (2-iodophenoxy) benzene mixing arrangement is used in production | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-214346097-U | Vortex formula 1, 3-difluoro-2- (2-iodophenoxy) benzene mixing arrangement is used in production | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-214346097-U | Vortex formula 1, 3-difluoro-2- (2-iodophenoxy) benzene mixing arrangement is used in production | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-214346508-U | 1, 3-difluoro-2- (2-iodophenoxy) benzene production is with biological safety cabinet convenient to remove | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-214346508-U | 1, 3-difluoro-2- (2-iodophenoxy) benzene production is with biological safety cabinet convenient to remove | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-214346508-U | 1, 3-difluoro-2- (2-iodophenoxy) benzene production is with biological safety cabinet convenient to remove | 石家庄久睿科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-213763173-U | Ultrasonic cleaning device is used in production of 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-213763173-U | Ultrasonic cleaning device is used in production of 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-213763173-U | Ultrasonic cleaning device is used in production of 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-213759594-U | Hot air disinfection cabinet for producing 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-213759594-U | Hot air disinfection cabinet for producing 1, 3-difluoro-2- (2-iodophenoxy) benzene | 石家庄久睿科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| US-10995072-B2 | Inhibitors of protease-activated receptor-2 | HEPTARES THERAPEUTICS LIMITED (GB) | 2021-05-04 | — | — | US | disclosed |
| US-20200140392-A1 | INHIBITORS OF PROTEASE-ACTIVATED RECEPTOR-2 | NXERA PHARMA UK LIMITED (GB) | 2020-05-07 | — | — | US | disclosed |
| US-10550089-B2 | Inhibitors of protease-activated receptor-2 | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190144394-A1 | INHIBITORS OF PROTEASE-ACTIVATED RECEPTOR-2 | HEPTARES THERAPEUTICS LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550089-B2 | Inhibitors of protease-activated receptor-2 | F2RL1, F2R, F2RL3 | SLC6A2 4732/4885HTR1A 438/4885KDM4E 4529/4885 |
| US-20190144394-A1 | INHIBITORS OF PROTEASE-ACTIVATED RECEPTOR-2 | F2RL1, F2R, F2RL3 | SLC6A2 4732/4885HTR1A 438/4885KDM4E 4529/4885 |
| US-10995072-B2 | Inhibitors of protease-activated receptor-2 | F2RL1, F2R, F2RL3 | SLC6A2 4398/4885HTR1A 497/4885KDM4E 4351/4885 |
| US-20200140392-A1 | INHIBITORS OF PROTEASE-ACTIVATED RECEPTOR-2 | F2RL1, F2R, F2RL3 | SLC6A2 4398/4885HTR1A 497/4885KDM4E 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.