Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575661 | 0.93 | CA2 (0.48) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL19575495 | 0.93 | CA1 (0.40) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL20973100 | 0.92 | CA1 (0.39) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL20975239 | 0.89 | HDAC1 (0.43) | HDAC1HDAC6ADORA2AADORA1TMIGD3 | |
| SCHEMBL20974973 | 0.89 | HDAC1 (0.38) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL24228118 | 0.85 | KDM4E (0.34) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL26229054 | 0.84 | CTSL (0.41) | ADORA2AADORA1TMIGD3 | |
| SCHEMBL20972947 | 0.83 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL20975405 | 0.83 | HDAC1 (0.32) | CA1CA2CA9CA4HDAC1 | |
| SCHEMBL19575499 | 0.83 | CCNE1 (0.40) | HDAC1HDAC6ADORA2AADORA1TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452477-B1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B C I PHARMA (BE) | 2023-09-13 | — | — | EP | disclosed |
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | B.C.I. PHARMA (BE) | 2022-02-01 | — | — | US | disclosed |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11236093-B2 | Adenine derivatives as protein kinase inhibitors | ADK, TNNI3K, TNK2 | CA1 4385/4885CA2 959/4885CA9 3381/4885 |
| US-20190127379-A1 | ADENINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | ADK, TNNI3K, TNK2 | CA1 4385/4885CA2 959/4885CA9 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.