⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19908752 | 0.79 | MMP8 (0.31) | — | |
| SCHEMBL22140493 | 0.76 | — | — | |
| SCHEMBL29846252 | 0.75 | — | — | |
| SCHEMBL19784259 | 0.75 | — | — | |
| SCHEMBL11428776 | 0.75 | FDPS (0.32) | — | |
| SCHEMBL14063426 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL22664270 | 0.72 | — | — | |
| SCHEMBL24783184 | 0.68 | — | — | |
| SCHEMBL21758397 | 0.67 | — | — | |
| SCHEMBL1679017 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384051-B2 | Ionizable compounds and compositions and uses thereof | NITTO DENKO CORPORATION (JP) | 2022-07-12 | — | — | US | disclosed |
| US-20190127318-A1 | IONIZABLE COMPOUNDS AND COMPOSITIONS AND USES THEREOF | NITTO DENKO CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |