Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 20/20 | 0.74 |
| ▸ | AVPR1A | P37288 | 20/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | OXTR | P30559 | 1/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19578044 | 1.00 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19577978 | 1.00 | AVPR2 (0.74) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19552149 | 0.95 | AVPR2 (0.66) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19552151 | 0.95 | AVPR2 (0.66) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL23752045 | 0.94 | AVPR2 (0.65) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL22365748 | 0.94 | AVPR2 (0.65) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL22365749 | 0.94 | AVPR2 (0.65) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL20974811 | 0.93 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19577924 | 0.93 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 | |
| SCHEMBL19577813 | 0.93 | AVPR2 (0.73) | AVPR2AVPR1ASLC6A2OXTROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253557-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-08-19 | — | — | US | disclosed |
| US-20190144422-A1 | HYDROXYALKYL-SUBSTITUTED HETEROARYLTRIAZOLE DERIVATIVES AND USES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2019-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253557-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND USES THEREOF | GLS, TNNI3, CYP11B2 | AVPR2 1574/4885AVPR1A 2827/4885SLC6A2 2193/4885 |
| US-20190144422-A1 | HYDROXYALKYL-SUBSTITUTED HETEROARYLTRIAZOLE DERIVATIVES AND USES THEREOF | AADAC, LIPG, HHAT | AVPR2 2683/4885AVPR1A 4165/4885SLC6A2 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.