Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.35 |
| ▸ | RARG | P13631 | 6/20 | 0.35 |
| ▸ | RARA | P10276 | 6/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 8/20 | 0.34 |
| ▸ | RXRB | P28702 | 6/20 | 0.34 |
| ▸ | RXRG | P48443 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29271029 | 0.99 | THRB (0.44) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL12160878 | 0.85 | MEN1 (0.46) | THRBMEN1LMNAMAPTRECQL | |
| Iodide SCHEMBL1051835 | 0.85 | MEN1 (0.46) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL22664031 | 0.84 | MEN1 (0.45) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL19063420 | 0.82 | MEN1 (0.40) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL3868600 | 0.82 | TDP1 (0.40) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL3867446 | 0.81 | TDP1 (0.39) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL136801 | 0.81 | MAPT (0.39) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL22435923 | 0.81 | HTT (0.43) | THRBMEN1LMNAMAPTRECQL | |
| SCHEMBL22663826 | 0.80 | MEN1 (0.39) | THRBMEN1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11526077-B2 | Positive photoresist composition, via-forming method, display substrate and display device | Beijing Boe Technology Development Co., Ltd. (CN) | 2022-12-13 | — | — | US | disclosed |
| US-20200225582-A9 | POSITIVE PHOTORESIST COMPOSITION, VIA-FORMING METHOD, DISPLAY SUBSTRATE AND DISPLAY DEVICE | Beijing Boe Technology Development Co., Ltd. (CN) | 2020-07-16 | — | — | US | disclosed |
| US-20190146341-A1 | POSITIVE PHOTORESIST COMPOSITION, VIA-FORMING METHOD, DISPLAY SUBSTRATE AND DISPLAY DEVICE | BOE TECHNOLOGY GROUP CO LTD (CN) | 2019-05-16 | — | — | US | disclosed |