Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 5/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 5/20 | 0.32 |
| ▸ | RARG | P13631 | 5/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868600 | 0.96 | TDP1 (0.40) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL3877735 | 0.91 | TDP1 (0.42) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL5268110 | 0.91 | MEN1 (0.39) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL4640722 | 0.89 | MAPT (0.39) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL22664031 | 0.86 | MEN1 (0.45) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL136801 | 0.86 | MAPT (0.39) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL12146331 | 0.85 | MEN1 (0.56) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL12160878 | 0.85 | MEN1 (0.46) | TDP1MEN1LMNAMAPTTHRB | |
| SCHEMBL19063420 | 0.84 | MEN1 (0.40) | TDP1MEN1LMNAMAPTTHRB | |
| Iodide SCHEMBL1051835 | 0.84 | MEN1 (0.46) | TDP1MEN1LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168492-B1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING SPA (IT) | 2025-12-24 | — | — | EP | disclosed |
| US-20250084066-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING S.P.A. (IT) | 2025-03-13 | — | — | US | disclosed |
| US-12187708-B2 | Near-infrared cyanine dyes and conjugates thereof | BRACCO IMAGING S.P.A. (IT) | 2025-01-07 | — | — | US | disclosed |
| US-20240083880-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING S.P.A. (IT) | 2024-03-14 | — | — | US | disclosed |
| WO-2024023138-A2 | CA-IX TARGETING FLUORESCENT PROBES | BRACCO IMAGING SPA (IT) | 2024-02-01 | — | — | WO | disclosed |
| US-11851421-B2 | Near-infrared cyanine dyes and conjugates thereof | BRACCO IMAGING S.P.A. (IT) | 2023-12-26 | — | — | US | disclosed |
| US-20230312523-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING S.P.A. (IT) | 2023-10-05 | — | — | US | disclosed |
| EP-4234634-A2 | MODIFIED CYANINE DYES AND CONJUGATES THEREOF | Bracco Imaging SPA (IT) | 2023-08-30 | — | — | EP | disclosed |
| CN-116209722-A | Near infrared cyanine dyes and conjugates thereof | 伯拉考成像股份公司 | 2023-06-02 | — | — | CN | disclosed |
| EP-4168492-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | Bracco Imaging SPA (IT) | 2023-04-26 | — | — | EP | disclosed |
| US-20050249668-A1 | Nir-fluorescent cyanine dyes, their synthesis and biological use | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-11-10 | — | — | US | disclosed |
| EP-1532988-A2 | Antibody dye conjugates for the intraoperative delimitation of tumors | Schering AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| EP-1176987-B1 | SHORT-CHAIN PEPTIDE DYE CONJUGATES USED AS CONTRAST AGENTS FOR OPTICAL DIAGNOSTICS | DIAGNOSTIKFORSCHUNG INST (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6630570-B1 | Of tumor cells and tissues; derived from vaso-active intestinal protein, somatostatin or neurotensin; methine/cyanine; useful for endoscopy | Insitut für Diagnostikforschung GmbH (DE) | 2003-10-07 | — | — | US | disclosed |
| US-20030095924-A1 | Galenical formulations | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-22 | — | — | US | disclosed |
| EP-1281405-A2 | Short-chained peptide-dye conjugates as contrast agents for optical diagnosis | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2003-02-05 | — | — | EP | disclosed |
| US-6447749-B1 | Perfluoro-alkyl containing dye molecules and galencial formulations | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-09-10 | — | — | US | disclosed |
| EP-1088559-A2 | Galenic formulations | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 2001-04-04 | — | — | EP | disclosed |
| US-5397690-A | Near-infrared absorbing dyes prepared from stenhouse salts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0591820-A1 | Near-infrared absorbing dyes prepared from Stenhouse salts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083880-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | IK, CIT, HCCS | TDP1 2523/4885MEN1 453/4885LMNA 3231/4885 |
| US-20050249668-A1 | Nir-fluorescent cyanine dyes, their synthesis and biological use | HCCS, MTHFD1, FOLR2 | TDP1 3885/4885MEN1 381/4885LMNA 4715/4885 |
| US-20230312523-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | HCCS, C1R, CYTH3 | TDP1 3622/4885MEN1 602/4885LMNA 1678/4885 |
| US-11851421-B2 | Near-infrared cyanine dyes and conjugates thereof | HCCS, C1R, CYTH3 | TDP1 3622/4885MEN1 602/4885LMNA 1678/4885 |
| US-20030095924-A1 | Galenical formulations | GALR1, GALR2, LGALS1 | TDP1 2074/4885MEN1 1210/4885LMNA 759/4885 |
| US-20250084066-A1 | NEAR-INFRARED CYANINE DYES AND CONJUGATES THEREOF | IK, CIT, HCCS | TDP1 2523/4885MEN1 453/4885LMNA 3231/4885 |
| US-12187708-B2 | Near-infrared cyanine dyes and conjugates thereof | IK, CIT, HCCS | TDP1 2523/4885MEN1 453/4885LMNA 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.