Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | RXRA | P19793 | 4/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640722 | 0.96 | MAPT (0.39) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3868600 | 0.89 | TDP1 (0.40) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3867446 | 0.86 | TDP1 (0.39) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL12160878 | 0.85 | MEN1 (0.46) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL22664031 | 0.84 | MEN1 (0.45) | MAPTTHRBRECQLMEN1LMNA | |
| Iodide SCHEMBL2587637 | 0.84 | MEN1 (0.48) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL3877735 | 0.84 | TDP1 (0.42) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL29271029 | 0.82 | THRB (0.44) | MAPTTHRBRECQLMEN1LMNA | |
| SCHEMBL19063420 | 0.82 | MEN1 (0.40) | MAPTTHRBRECQLMEN1LMNA | |
| Iodide SCHEMBL1051835 | 0.82 | MEN1 (0.46) | MAPTTHRBRECQLMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2024-04-25 | — | — | US | disclosed |
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11578093-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| EP-3030683-B1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES CALIFORNIA INC (US) | 2022-03-02 | — | — | EP | disclosed |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-10800805-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10787573-B2 | Multimeric protected fluorescent reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-20190309171-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| WO-2015021079-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-02-12 | — | — | WO | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-8669374-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2014-03-11 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012027623-A2 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012027618-A2 | FUNCTIONALIZED CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132948-A1 | Cyanine Dyes | ABCG2, IK, ACR | MAPT 2014/4885THRB 4656/4885RECQL 3487/4885 |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | MAPT 2250/4885THRB 4333/4885RECQL 522/4885 |
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | MAPT 2014/4885THRB 4656/4885RECQL 3487/4885 |
| US-11578093-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | MAPT 2250/4885THRB 4333/4885RECQL 522/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | MAPT 2014/4885THRB 4656/4885RECQL 3487/4885 |
| US-10800805-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | MAPT 2250/4885THRB 4333/4885RECQL 522/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | MAPT 2014/4885THRB 4656/4885RECQL 3487/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | MAPT 2014/4885THRB 4656/4885RECQL 3487/4885 |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | MAPT 2250/4885THRB 4333/4885RECQL 522/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | MAPT 1605/4885THRB 4392/4885RECQL 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.