Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | FGF1 | P05230 | 1/20 | 0.32 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.32 |
| ▸ | MARS1 | P56192 | 4/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.31 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.30 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513195 | 0.81 | FGF1 (0.39) | TLR4F10FGF1CD209LGALS3 | |
| SCHEMBL20976854 | 0.76 | TLR4 (0.36) | TLR4F10FGF1CD209LGALS3 | |
| SCHEMBL19273656 | 0.68 | PRKD3 (0.45) | TLR4LGALS3PRKD3PRKCGPRKCB | |
| SCHEMBL20976829 | 0.67 | ALDH1A1 (0.31) | MARS1 | |
| SCHEMBL29344800 | 0.66 | CD209 (0.49) | F10FGF1CD209LGALS3ENGASE | |
| SCHEMBL15316732 | 0.66 | LGALS3 (0.55) | FGF1CD209LGALS3ENGASELGALS9 | |
| SCHEMBL16688327 | 0.65 | CD209 (0.54) | FGF1CD209LGALS3ENGASELGALS9 | |
| SCHEMBL13290316 | 0.65 | CD209 (0.60) | FGF1CD209LGALS3ENGASELGALS9 | |
| SCHEMBL17830236 | 0.65 | CD209 (0.60) | FGF1CD209LGALS3ENGASELGALS9 | |
| SCHEMBL6815714 | 0.65 | CD209 (0.60) | FGF1CD209LGALS3ENGASELGALS9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3335045-B1 | COMPOSITIONS AND METHODS | DIAGNOSTIG LTD (GB) | 2019-05-08 | — | — | EP | disclosed |