Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978940 | 0.69 | KDM4C (0.65) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL20978732 | 0.68 | KDM4C (0.44) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL20978917 | 0.68 | KDM4C (0.67) | KDM4CKDM2BKDM5ADHFRPHF8 | |
| SCHEMBL16033390 | 0.65 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL20979024 | 0.63 | KDM4C (0.45) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL1483164 | 0.59 | DHFR (0.44) | KDM4CKDM2BDHFR | |
| SCHEMBL1577408 | 0.58 | DHFR (0.41) | KDM4CKDM2BDHFRSLC6A4 | |
| SCHEMBL20978851 | 0.57 | KDM4C (0.73) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL16034821 | 0.56 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8 | |
| SCHEMBL1483024 | 0.56 | DHFR (0.43) | KDM4CKDM2BDHFRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |