Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978732 | 0.83 | KDM4C (0.44) | KDM4CPOLBPHF8KDM2AKDM2B | |
| SCHEMBL20979071 | 0.64 | KDM4C (0.72) | KDM4CPHF8KDM2BKDM5AKDM5B | |
| SCHEMBL20978946 | 0.64 | KDM4C (0.64) | KDM4CPHF8KDM2BKDM5AKDM5B | |
| SCHEMBL16033932 | 0.62 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL20978980 | 0.62 | KDM4C (0.55) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL20978965 | 0.61 | KDM4C (0.72) | KDM4CPHF8KDM2BKDM5AKDM5B | |
| SCHEMBL20978717 | 0.61 | KDM4C (0.63) | KDM4CKDM2AKDM2BKDM5AKDM5B | |
| SCHEMBL16033821 | 0.58 | KDM4C (1.00) | KDM4CPHF8KDM2BKDM5AKDM5B | |
| SCHEMBL16034492 | 0.58 | KDM4C (1.00) | KDM4CKDM2BKDM5AKDM5B | |
| SCHEMBL16094879 | 0.58 | KDM4C (0.61) | KDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |