Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.44 |
| ▸ | KDM5A | P29375 | 4/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979024 | 0.83 | KDM4C (0.45) | KDM4CKDM5AKDM5BKDM2BPOLB | |
| SCHEMBL20979071 | 0.78 | KDM4C (0.72) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL20978883 | 0.68 | KDM4C (0.48) | KDM4CKDM5AKDM2BPHF8 | |
| SCHEMBL20978980 | 0.63 | KDM4C (0.55) | KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL20978717 | 0.62 | KDM4C (0.63) | KDM4CKDM5AKDM5BKDM2BKDM2A | |
| SCHEMBL20979070 | 0.62 | KDM4C (0.72) | KDM4CKDM5AKDM5BKDM2BPHF8 | |
| SCHEMBL16034492 | 0.62 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL20978867 | 0.61 | CNR1 (0.38) | — | |
| SCHEMBL16094879 | 0.58 | KDM4C (0.61) | KDM4CKDM5AKDM5B | |
| SCHEMBL16033547 | 0.58 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |