Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.52 |
| ▸ | KDM4A | O75164 | 4/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.47 |
| ▸ | KDM5A | P29375 | 7/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979046 | 0.92 | KDM5B (0.48) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978948 | 0.91 | KDM5A (0.52) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20979019 | 0.89 | KDM5B (0.45) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20979004 | 0.88 | KDM2B (0.49) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978753 | 0.84 | KDM4C (0.52) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL16075663 | 0.83 | KDM4C (0.74) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL16075681 | 0.82 | KDM4C (0.60) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL16078953 | 0.79 | KDM4C (0.69) | KDM4CKDM4AKDM5BKDM5AKDM2B | |
| SCHEMBL20978901 | 0.76 | KDM4C (0.55) | KDM4CKDM4AKDM5BKDM5A | |
| SCHEMBL20978893 | 0.74 | KDM2B (0.65) | KDM4CKDM4AKDM5BKDM5AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |