Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.54 |
| ▸ | KDM5A | P29375 | 8/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 3/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033757 | 0.79 | KDM5A (0.82) | KDM5BKDM5AKDM4CKDM2BKDM4A | |
| SCHEMBL20978802 | 0.77 | KDM4C (0.41) | KDM5BKDM5AKDM4CKDM2BKDM4E | |
| SCHEMBL20979029 | 0.77 | KDM4C (0.50) | KDM5BKDM5AKDM4CKDM4EKDM5C | |
| SCHEMBL20978930 | 0.76 | EPHX2 (0.41) | KDM5BKDM5AKDM4CKDM2BKDM4E | |
| SCHEMBL20978805 | 0.75 | KDM5B (0.59) | KDM5BKDM5AKDM4CKDM2BKDM4E | |
| SCHEMBL20978848 | 0.74 | KDM4C (0.52) | KDM5BKDM5AKDM4CKDM4EKDM5C | |
| SCHEMBL16095432 | 0.74 | KDM5B (0.50) | KDM5BKDM5AKDM4CKDM2BKDM4E | |
| SCHEMBL20978910 | 0.74 | KDM5A (0.60) | KDM5BKDM5AKDM4CKDM2BKDM4E | |
| SCHEMBL20978783 | 0.73 | KDM2B (0.64) | KDM5BKDM5AKDM4CKDM2BJMJD6 | |
| SCHEMBL20978807 | 0.72 | KDM5B (0.62) | KDM5BKDM5AKDM4CKDM2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |