Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.47 |
| ▸ | KDM5A | P29375 | 6/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979046 | 0.89 | KDM5B (0.48) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978948 | 0.88 | KDM5A (0.52) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978701 | 0.88 | KDM4C (0.52) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20979019 | 0.85 | KDM5B (0.45) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16075664 | 0.84 | KDM2B (0.69) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16075679 | 0.83 | KDM2B (0.56) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL17710642 | 0.81 | KDM2B (0.65) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16078936 | 0.81 | KDM4C (0.73) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16075670 | 0.75 | KDM4C (0.57) | KDM2BKDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978893 | 0.74 | KDM2B (0.65) | KDM2BKDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |