Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809460 | 0.85 | PLA2G2C (0.40) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL10617027 | 0.85 | PLA2G2C (0.40) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL200456 | 0.85 | PLA2G2C (0.40) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL21151131 | 0.83 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL19705849 | 0.83 | FOLH1 (0.42) | FOLH1NAALAD2RIMKLAGABRPGABRD | |
| SCHEMBL24629267 | 0.82 | CTSK (0.38) | LMNASLC15A2KDM4E | |
| SCHEMBL23446445 | 0.82 | CTSK (0.38) | LMNASLC15A2KDM4E | |
| SCHEMBL12295242 | 0.82 | PLA2G2C (0.44) | LMNA | |
| SCHEMBL14240724 | 0.82 | PLA2G2C (0.44) | LMNA | |
| SCHEMBL15765338 | 0.78 | DPP4 (0.46) | FOLH1NAALAD2RIMKLALMNAGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057991-B1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RES (US) | 2019-05-08 | — | — | EP | disclosed |