SCHEMBL2097905

SCHEMBL2097905

CC(C)(C)c1cc([Si](C)(C)CCCCl)ccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
ALOX15 P16050 2/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 1/20 0.43
CYP2C9 P11712 1/20 0.43
MIF P14174 1/20 0.43
TYR P14679 1/20 0.43
HTT P42858 1/20 0.43
NFE2L2 Q16236 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
ATP2A2 P16615 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATP2A3 Q93084 1/20 0.37
HSP90AA1 P07900 2/20 0.36
HSP90AB1 P08238 2/20 0.36
ATM Q13315 2/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9633698 0.74 NR1H2 (0.46) LMNATYRSMN1; SMN2ATML3MBTL1
Methane SCHEMBL27469130 0.72 NR1H2 (0.45) LMNATYRSMN1; SMN2ATML3MBTL1
SCHEMBL9631526 0.69 ALDH1A1 (0.35) ALDH1A1LMNAHTTHSD17B10KDM4E
SCHEMBL9632610 0.68 ALDH1A1 (0.38) ALDH1A1ATMGAAL3MBTL1TSHR
SCHEMBL7524511 0.68 ALDH1A1 (0.41) ALDH1A1ALOX15NR1I2LMNACYP2C9
SCHEMBL9633376 0.68 NR1H2 (0.39) ALDH1A1LMNACYP2C9KDM4ECYP1A2
SCHEMBL10822062 0.66 ALDH1A1 (0.55) ALDH1A1ALOX15NR1I2LMNACYP2C9
Methane SCHEMBL27264866 0.66 NR1H2 (0.38) ALDH1A1LMNACYP2C9KDM4ECYP1A2
SCHEMBL9656709 0.66 NR1H2 (0.41) NR1H2NR1H3
SCHEMBL3228612 0.65 MGAM (0.43) MAPTESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115161-B2 Process for producing polycarbonates and a coordination complex used therefor SK INNOVATION CO., LTD. (KR) 2015-08-25 US disclosed
EP-2573126-B1 A PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO LTD (KR) 2014-09-24 EP disclosed
US-8829156-B2 Process for producing polycarbonates and a coordination complex used therefor SK INNOVATION CO., LTD. (KR) 2014-09-09 US disclosed
US-20140249323-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO., LTD. (KR) 2014-09-04 US disclosed
EP-2147037-B1 A PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO LTD (KR) 2014-08-20 EP disclosed
US-8530615-B2 Process for producing polycarbonates and a coordination complex used therefor SK INNOVATION CO., LTD. (KR) 2013-09-10 US disclosed
EP-2573126-A1 A process for producing polycarbonates and a coordination complex used therefor SK Innovation Co. Ltd. (KR) 2013-03-27 EP disclosed
US-20120226016-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO., LTD. (KR) 2012-09-06 US disclosed
US-20120184709-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO., LTD. (KR) 2012-07-19 US disclosed
US-8163867-B2 Process for producing polycarbonates and a coordination complex used therefor SK INNOVATION CO., LTD. (KR) 2012-04-24 US disclosed
US-20100121026-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK INNOVATION CO., LTD. (KR) 2010-05-13 US disclosed
EP-2147037-A1 A PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK Energy Co., Ltd. (KR) 2010-01-27 EP disclosed
WO-2008136591-A1 A PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR SK ENERGY CO., LTD. (KR) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120184709-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR NOTUM, WEE1, WEE2 ALDH1A1 3221/4885ALOX15 41/4885NR1I2 4410/4885
US-20140249323-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR NOTUM, WEE1, WEE2 ALDH1A1 3221/4885ALOX15 41/4885NR1I2 4410/4885
US-20100121026-A1 PROCESS FOR PRODUCING POLYCARBONATES AND A COORDINATION COMPLEX USED THEREFOR NOTUM, WEE1, TECR ALDH1A1 3948/4885ALOX15 58/4885NR1I2 4590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.