SCHEMBL9633698

SCHEMBL9633698

CC(C)(C)c1ccc([Si](C)(C)CCCCl)cc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 4/20 0.46
NR1H3 Q13133 4/20 0.46
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 1/20 0.35
TYR P14679 1/20 0.34
BCHE P06276 8/20 0.34
ACHE P22303 8/20 0.34
KIF11 P52732 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27469130 0.98 NR1H2 (0.45) NR1H2NR1H3LMNAPOLBRAB9A
SCHEMBL8522012 0.80 TSHR (0.41) NR1H2NR1H3LMNAPOLBRAB9A
SCHEMBL9662228 0.79 NR1H2 (0.47) NR1H2NR1H3LMNAL3MBTL1KIF11
SCHEMBL9633376 0.79 NR1H2 (0.39) NR1H2NR1H3LMNAKCNH2
SCHEMBL9656709 0.77 NR1H2 (0.41) NR1H2NR1H3ACHE
Methane SCHEMBL27264866 0.77 NR1H2 (0.38) NR1H2NR1H3LMNA
SCHEMBL3228612 0.76 MGAM (0.43) NR1H2NR1H3
SCHEMBL2097905 0.74 ALDH1A1 (0.43) NR1H2NR1H3LMNAATML3MBTL1
SCHEMBL9661228 0.73 NR1H2 (0.38) NR1H2NR1H3LMNAPOLBKCNH2
SCHEMBL9663938 0.72 NR1H2 (0.37) NR1H2NR1H3LMNATSHRKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313353-B1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI DOWELANCO (US) 1992-06-17 EP disclosed
US-4927812-A FUNGICIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-05-22 US disclosed
WO-1989003640-A1 MORPHOLINYL SILANES AND USE FOR CONTROL OF PLANT DISEASES CAUSED BY FUNGI THE DOW CHEMICAL COMPANY (US) 1989-05-05 WO disclosed
EP-0313353-A1 Morpholinyl silanes and use for control of plant diseases caused by fungi DOWELANCO (US) 1989-04-26 EP disclosed