Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633376 | 0.82 | NR1H2 (0.39) | NR1H2NR1H3MGAM | |
| Methane SCHEMBL27264866 | 0.80 | NR1H2 (0.38) | NR1H2NR1H3MGAM | |
| SCHEMBL5736639 | 0.79 | — | — | |
| SCHEMBL3228612 | 0.79 | MGAM (0.43) | NR1H2NR1H3MGAM | |
| SCHEMBL7863483 | 0.79 | ACHE (0.36) | NR1H2NR1H3ACHESLC2A1 | |
| SCHEMBL9633698 | 0.77 | NR1H2 (0.46) | NR1H2NR1H3ACHE | |
| SCHEMBL9661228 | 0.76 | NR1H2 (0.38) | NR1H2NR1H3 | |
| Methane SCHEMBL27469130 | 0.76 | NR1H2 (0.45) | NR1H2NR1H3ACHE | |
| SCHEMBL2007623 | 0.75 | TAAR1 (0.41) | NR1H2NR1H3ACHESLC2A1 | |
| SCHEMBL10946243 | 0.75 | ACHE (0.33) | ACHESLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472304-A2 | Pharmaceutical compositions containing therapeutically active organosilane derivatives and process for preparing same | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1992-02-26 | — | — | EP | disclosed |